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S.E.M.I.: Side Effects May Include...

IGDB0.0/10Playlogs—Hack and slash/Beat 'em upReleased: Jan 23, 2026Two Horn Unicorn

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About This Game

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Events Featured In (1)

INDIE Live Expo 2025.11.29

29 November 2025 at 18:00

11/29/2025, 9:00:00 AM

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Game Info

Developer
Two Horn Unicorn
Publisher
Two Horn Unicorn
Release Date
Jan 23, 2026
Platforms
  • PC (Microsoft Windows)
IGDB
0.0/10
Playlogs
No ratings yet

Genre

Hack and slash/Beat 'em upIndie

Themes

PartyActionComedy

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Releases

  • PC (Microsoft Windows)Nov 20, 2025

Supported Languages

AudioSubtitlesInterface
  • English:✓✓
  • Chinese (Simplified):✓✓
  • Dutch:✓✓
  • English (UK):✓✓
  • French:✓✓

Player perspectives

  • Third person

Multiplayer

  • Online co-op (4)

Game engine

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